Why this project is important for me
Over the last 7 years I have been working on severe diseases affecting the liver, particularly on non-alcoholic steatohepatitis, currently the most common liver disease worldwide. This disease has ...
The microarray: a simple tool with a great potential!
It has been calculated that microRNAs regulate up to 1/3 of all human genes. This complex regulation system, where 1 microRNA can switch on or off many different genes, is often responsible for man...
A very interesting interview to Dr. David R. Brigstock on extracellular vesicles and scarring of the liver.
http://pediatricsnationwide.org/2015/04/25/fightin...Feel free to ask questions on this or any other EV-related topic.Thank you!
The first step: microRNAs
The role of small non-coding microRNA (miRNAs) has become essential for gene regulation in a variety of human diseases. In this short video, expression and function of miRNAs is nicely explained! ...
Our beautiful Lab!!
Beneficial effect of iPSC-extracellular vesicles (iPSC-EV)
Extracellular vesicles derived from stem cell (iPSC) have a beneficial effect on liver malignant cells (hepatic stellate cell, HSC) responsible for the scarring of the liver (process called fibrosi...
Generation of iPSC
How a iPSC-derived extracellular vesicle looks like!
Generation of human inducible pluripotent stem cells (iPSC)
http://www.nature.com/nprot/journal/v3/n7/full/npr...In this report, In-Hyun Park and colleagues explained how to generate human-induced pluripotent stem cells. This was an extremely important disc...
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